We are leading large-scale efforts in single-cell transcriptional profiling in clinical gliomas in adults with our collaborators at the Broad Institute. These efforts
We are extending our single-cell genomics efforts to multi-omics approaches to shed further light on regulatory programs and cellular trajectories in gliomas
We developed an integrative approach to understand glioblastoma cellular states, combining scRNA-seq of >30 glioblastoma samples and patient-derived xenografts (PDX),